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KMID : 1144320120440060485
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감염과 화학요법
2012 Volume.44 No. 6 p.485 ~ p.490
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Rifampin-resistant Relapsed Tuberculosis Confirmed by Molecular Technique
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Moon Song-Mi
Lee Sang-Oh
Choi Sang-Ho
Kim Yang-Soo
Woo Jun-Hee
Kim Sung-Han
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Abstract
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Recurrent tuberculosis can be caused by a relapse of the original infecting strain, a reinfection with a new strain of Mycobacterium tuberculosis or a paradoxical response associated with the anti-tuberculosis treatment. A drug susceptibility test is important when evaluating recurrent tuberculosis but a conventional microbiological test may be unavailable or unsuccessful. Recently, direct molecular testing as a line probe assay (GenoType® MTBDRplus, Hain Lifescience GmbH, Nehren, Germany) has shown promising results for the diagnosis or treatment of drug-resistant tuberculosis. We present two cases of rifampin-resistant, relapsed tuberculosis that were confirmed using a molecular technique.
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KEYWORD
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Mycobacterium tuberculosis, Rifampin, Drug resistance
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